ITC

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Browse ITC data

For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

DatumProteinLigandΔG (kJ/mol)ΔH (kJ/mol)TΔS (kJ/mol)KD (µM)ΔCp (J/mol)
Link Disabled Homolog 1 (native) TKSMNFDNPVYRKT TKSMNFDNPVYRKT diagram
TKSMNFDNPVYRKT
-32.22 -40.17 -7.95 3.0
Link Disabled Homolog 1 (H81A) TKSMNFDNPVYRKT TKSMNFDNPVYRKT diagram
TKSMNFDNPVYRKT
-46.86 -48.53 -1.67 3.2
Link Disabled Homolog 1 (H81Q) TKSMNFDNPVYRKT TKSMNFDNPVYRKT diagram
TKSMNFDNPVYRKT
-33.05 -45.19 -12.13 1.6
Link Disabled Homolog 1 (K45A) TKSMNFDNPVYRKT TKSMNFDNPVYRKT diagram
TKSMNFDNPVYRKT
-32.22 -42.26 -10.04 2.3
Link Disabled Homolog 1 (K45Q) TKSMNFDNPVYRKT TKSMNFDNPVYRKT diagram
TKSMNFDNPVYRKT
-31.38 -33.89 -2.51 2.9
Link Disabled Homolog 1 (K45E) TKSMNFDNPVYRKT TKSMNFDNPVYRKT diagram
TKSMNFDNPVYRKT
-32.22 -44.35 -12.13 2.2
Link Disabled Homolog 1 (K82A) TKSMNFDNPVYRKT TKSMNFDNPVYRKT diagram
TKSMNFDNPVYRKT
-33.47 -46.02 -12.55 1.4
Link Disabled Homolog 1 (K82Q) TKSMNFDNPVYRKT TKSMNFDNPVYRKT diagram
TKSMNFDNPVYRKT
-33.05 -60.67 -27.61 1.7
Link Disabled Homolog 1 (K45A/K82A) TKSMNFDNPVYRKT TKSMNFDNPVYRKT diagram
TKSMNFDNPVYRKT
-31.38 -36.82 -5.44 3.0
Link Disabled Homolog 1 (K45Q/K82Q) TKSMNFDNPVYRKT TKSMNFDNPVYRKT diagram
TKSMNFDNPVYRKT
-31.8 -38.91 -7.11 2.7
Link Disabled Homolog 1 (K45E/K82Q) TKSMNFDNPVYRKT TKSMNFDNPVYRKT diagram
TKSMNFDNPVYRKT
-32.22 -42.68 -10.46 2.1
Link Disabled Homolog 1 (native) D-myo-inositol-1,4,5-triphosphate D-myo-inositol-1,4,5-triphosphate diagram
D-myo-inositol-1,4,5-triphosphate
-33.89 -80.33 -46.44 1.2
Link Disabled Homolog 1 (H81A) D-myo-inositol-1,4,5-triphosphate D-myo-inositol-1,4,5-triphosphate diagram
D-myo-inositol-1,4,5-triphosphate
-27.61 -46.86 -19.25 24.0
Link Disabled Homolog 1 (H81Q) D-myo-inositol-1,4,5-triphosphate D-myo-inositol-1,4,5-triphosphate diagram
D-myo-inositol-1,4,5-triphosphate
-26.78 -41.0 -14.23 18.0
Link Disabled Homolog 1 (S114Y) D-myo-inositol-1,4,5-triphosphate D-myo-inositol-1,4,5-triphosphate diagram
D-myo-inositol-1,4,5-triphosphate
-33.89 -102.09 -68.2 1.2
Link Disabled Homolog 1 (F158V) D-myo-inositol-1,4,5-triphosphate D-myo-inositol-1,4,5-triphosphate diagram
D-myo-inositol-1,4,5-triphosphate
-35.56 -75.73 -40.17 0.6