ITC

Browse

ISMB logo
Biochemical Journal logo

Browse ITC data

For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

< >

DatumProteinLigandΔG (kJ/mol)ΔH (kJ/mol)TΔS (kJ/mol)KD (µM)ΔCp (J/mol)
Link c-Src SH2 Domain Compound 7, charifson et al. Compound 7, charifson et al. diagram
Compound 7, charifson et al. 		-32.64 -19.25 13.35 2.3
Link c-Src SH2 Domain Compound 8, charifson et al. Compound 8, charifson et al. diagram
Compound 8, charifson et al. 		-42.26 -28.45 13.72 0.05
Link c-Src SH2 Domain Compound 9, charifson et al. Compound 9, charifson et al. diagram
Compound 9, charifson et al. 		-41.0 -25.94 14.97 0.09
Link c-Src SH2 Domain [acetyl]-[deoxy-difluoromethelene-phosphotyrosine]-E-[dipentylamine] [acetyl]-[deoxy-difluoromethelene-phosphotyrosine]-E-[dipentylamine] diagram
[acetyl]-[deoxy-difluoromethelene-phosphotyrosine]-E-[dipentylamine] 		-32.64 -21.34 11.23 2.4
Link c-Src SH2 Domain acetyl-pYYE-butylpiperidine acetyl-pYYE-butylpiperidine diagram
acetyl-pYYE-butylpiperidine 		-35.15 -22.59 12.47 1.0
Link c-Src SH2 Domain acetyl-pYYE-dipentylamine acetyl-pYYE-dipentylamine diagram
acetyl-pYYE-dipentylamine 		-37.24 -17.99 19.09 0.4
Link c-Src SH2 Domain acetyl-pYYE-methyl(cyclopentyl-propyl)amine acetyl-pYYE-methyl(cyclopentyl-propyl)amine diagram
acetyl-pYYE-methyl(cyclopentyl-propyl)amine 		-36.82 -29.71 7.11 0.4
Link c-Src SH2 Domain (C188A) Compound 13, charifson et al. Compound 13, charifson et al. diagram
Compound 13, charifson et al. 		-35.56 -7.53 27.82 0.6
Link v-Src SH2 Domain (R207A) PQpYEEIPI PQpYEEIPI diagram
PQpYEEIPI 		-35.15 -30.96 4.18 0.67
Link v-Src SH2 Domain (R207A) PQpYEpYIPI PQpYEpYIPI diagram
PQpYEpYIPI 		-38.49 -30.96 7.53 0.17
Link v-Src SH2 Domain (R207A) PQpYIpYVPI PQpYIpYVPI diagram
PQpYIpYVPI 		-32.22 -8.37 23.85 1.82
Link v-Src SH2 Domain (R207A) PpYEYIPI PpYEYIPI diagram
PpYEYIPI 		-34.31 -30.12 4.18 1.0
Link v-Src SH2 Domain (R207F) PQpYEEIPI PQpYEEIPI diagram
PQpYEEIPI 		-38.07 -33.05 4.6 0.19
Link v-Src SH2 Domain (R207F) PQpYEpYIPI PQpYEpYIPI diagram
PQpYEpYIPI 		-40.58 -28.03 12.55 0.08
Link v-Src SH2 Domain (R207F) PQpYIpYVPI PQpYIpYVPI diagram
PQpYIpYVPI 		-35.98 -7.11 28.87 0.42
Link v-Src SH2 Domain (R207F) PpYEYIPI PpYEYIPI diagram
PpYEYIPI 		-35.56 -30.12 5.44 0.63
Link v-Src SH2 Domain (variant 1) pYEEI pYEEI diagram
pYEEI 		-37.7 -25.36 12.35 0.24
Link v-Src SH2 Domain (variant 1) ptc-EEI ptc-EEI diagram
ptc-EEI 		-39.96 -18.74 21.21 0.1 -0.94
Link v-Src SH2 Domain (variant 1) xx1ptc-EEI xx1ptc-EEI diagram
xx1ptc-EEI 		-38.74 -20.96 17.84 0.16
Link v-Src SH2 Domain (variant 1) xx2ptc-EEI xx2ptc-EEI diagram
xx2ptc-EEI 		-41.0 -30.67 10.35 0.06 -0.89

1 .. 18 19 20 21