ITC datum
| Protein and Ligand | |||
|---|---|---|---|
| Protein name | c-Src SH2 Domain | ||
| Ligand name |
Compound 9, charifson et al.
 Compound 9, charifson et al. |
||
| Interaction type | Synthetic ligands | ||
| ITC data | ITC data | ||
| Structure data | Structure data | ||
| ITC Information | |||
| n | ± | ||
| ΔG | -41.0 | ± | kJ/mol |
| ΔH | -25.94 | ± 2.09 | kJ/mol |
| -TΔS | 14.97 | ± | kJ/mol |
| KD | 0.09 | ± 0.04 | uM |
| ΔCP | ± | ||
| Notes on error determination |
Not available |
General comments | |
| Warnings |
Rounding errors DeltaG (-41.00) != -R.T.ln(Ka) (-40.22). Tolerance range from -41.41 to -40.59 |
||
| Instrument | Microcal MCS Titration Calorimeter | ||
| Temp. (K) | 298.15 | pH | 8.0 |
| Buffer | HEPES 20.00 mM Sodium Chloride 150.00 mM | ||
| Cell content | Protein | ||
| Reference | Biochemistry [1997] 36, 6283-6293 | ||