ITC datum
Protein and Ligand | |||
---|---|---|---|
Protein name | c-Src SH2 Domain | ||
Ligand name |
Compound 13, charifson et al.
Compound 13, charifson et al. |
||
Interaction type | Synthetic ligands | ||
ITC data | ITC data | ||
Structure data | Structure data | ||
ITC Information | |||
n | ± | ||
ΔG | -38.07 | ± | kJ/mol |
ΔH | -51.04 | ± 0.42 | kJ/mol |
-TΔS | -12.85 | ± | kJ/mol |
KD | 0.2 | ± | uM |
ΔCP | ± | ||
Notes on error determination |
Not available |
General comments | |
Warnings |
Rounding errors |
||
Instrument | Microcal MCS Titration Calorimeter | ||
Temp. (K) | 298.15 | pH | 8.0 |
Buffer | HEPES 20.00 mM Sodium Chloride 150.00 mM | ||
Cell content | Protein | ||
Reference | Biochemistry [1997] 36, 6283-6293 |