ITC datum
| Protein and Ligand | |||
|---|---|---|---|
| Protein name | HIV-1 Protease (I13V/E35D/M36I/S37N/R41K/R57K/H69K/L89M) | ||
| Ligand name |
Indinavir
 Indinavir |
||
| Interaction type | Synthetic ligands | ||
| ITC data | ITC data | ||
| Structure data | Structure data | ||
| ITC Information | |||
| n | ± | ||
| ΔG | -48.53 | ± | kJ/mol |
| ΔH | 10.88 | ± | kJ/mol |
| -TΔS | 59.41 | ± | kJ/mol |
| KD | 0.0 | ± 0.0 | uM |
| ΔCP | ± | ||
| Notes on error determination |
Not available |
General comments |
Displacement titration experiments. Concentration of acetylpepstatin in the titration cell was 200 micromolar. |
| Warnings | |||
| Instrument | VP-ITC Microcalorimeter | ||
| Temp. (K) | 298.15 | pH | 5.0 |
| Buffer | DMSO 2.00 % Sodium Acetate 10.00 mM | ||
| Cell content | Protein | ||
| Reference | Biochemistry [2002] 41, 8613-8619 | ||