ITC datum
| Protein and Ligand | |||
|---|---|---|---|
| Protein name | Integrin Alpha-L | ||
| Ligand name |
1-acetyl-4-(4-{4-[(2-ethoxyphenyl)thio]-3-nitrophenyl}pyridin-2-yl)piperazine
![1-acetyl-4-(4-{4-[(2-ethoxyphenyl)thio]-3-nitrophenyl}pyridin-2-yl)piperazine diagram](/ligand_diagrams/17.png) 1-acetyl-4-(4-{4-[(2-ethoxyphenyl)thio]-3-nitrophenyl}pyridin-2-yl)piperazine |
||
| Interaction type | Synthetic ligands | ||
| ITC data | ITC data | ||
| Structure data | Structure data | ||
| ITC Information | |||
| n | 1.12 | ± | |
| ΔG | -44.9 | ± | kJ/mol |
| ΔH | -32.22 | ± | kJ/mol |
| -TΔS | 12.68 | ± | kJ/mol |
| KD | 0.02 | ± | uM |
| ΔCP | ± | ||
| Notes on error determination |
Not applicable |
General comments | |
| Warnings | |||
| Instrument | VP-ITC Microcalorimeter | ||
| Temp. (K) | 303.15 | pH | 7.5 |
| Buffer | Sodium Chloride 150.00 mM Tris base 20.00 mM Magnesium Chloride 1.00 mM DMSO 2.00 % | ||
| Cell content | Protein | ||
| Reference | Biochemistry [2004] 43, 2394-2404 | ||