ITC datum
| Protein and Ligand | |||
|---|---|---|---|
| Protein name | Alpha-Thrombin | ||
| Ligand name |
[((1r)-2-{(2s)-2-[({4-[amino(imino)methyl]benzyl}amino)carbonyl]azetidinyl}-1-cyclohexyl-2-oxoethyl)amino]acetic acid
![[((1r)-2-{(2s)-2-[({4-[amino(imino)methyl]benzyl}amino)carbonyl]azetidinyl}-1-cyclohexyl-2-oxoethyl)amino]acetic acid diagram](/ligand_diagrams/24.png) [((1r)-2-{(2s)-2-[({4-[amino(imino)methyl]benzyl}amino)carbonyl]azetidinyl}-1-cyclohexyl-2-oxoethyl)amino]acetic acid |
||
| Interaction type | Synthetic ligands | ||
| ITC data | ITC data | ||
| Structure data | Structure data | ||
| ITC Information | |||
| n | ± | ||
| ΔG | -47.9 | ± | kJ/mol |
| ΔH | -37.0 | ± 1.2 | kJ/mol |
| -TΔS | 10.9 | ± | kJ/mol |
| KD | 0.0 | ± | uM |
| ΔCP | ± | ||
| Notes on error determination |
Not available |
General comments | |
| Warnings | |||
| Instrument | Microcal MCS Titration Calorimeter | ||
| Temp. (K) | 298.15 | pH | 7.8 |
| Buffer | Buffer Substance (Tris, Tris(hydroxymethyl)amino-methane; Tricine; N-tris(hydroxymethyl)methylglycine; Hepes; N-2-hydroxylethylpiperazine-N-2-ethanesulphonic acid; pyrophosphate) 50.00 mM PEG 8000 0.10 % Sodium Chloride Rubidium Chloride 100.00 mM | ||
| Cell content | Protein | ||
| Reference | J Mol Biol. [2001] 313, 593-614 | ||