| ITC comment | ITC comment defintion |
|---|
| Affinity (578.0347) greater than 313.4408. It is difficult to interpred ITC data if Affinity is greater than 313.4408 as the sigmoidal curve becomes too shallow. |
DUBIOUS_DATA |
| Affinity (580.0000) greater than 313.4408. It is difficult to interpred ITC data if Affinity is greater than 313.4408 as the sigmoidal curve becomes too shallow. |
DUBIOUS_DATA |
| Affinity (773.0887) greater than 313.4408. It is difficult to interpred ITC data if Affinity is greater than 313.4408 as the sigmoidal curve becomes too shallow. |
DUBIOUS_DATA |
| Affinity (833.3333) greater than 313.4408. It is difficult to interpred ITC data if Affinity is greater than 313.4408 as the sigmoidal curve becomes too shallow. |
DUBIOUS_DATA |
| Affinity (884.9558) greater than 313.4408. It is difficult to interpred ITC data if Affinity is greater than 313.4408 as the sigmoidal curve becomes too shallow. |
DUBIOUS_DATA |
| Affinity (909.0909) greater than 313.4408. It is difficult to interpred ITC data if Affinity is greater than 313.4408 as the sigmoidal curve becomes too shallow. |
DUBIOUS_DATA |
| Altered change in enthalpy and entropy from further studies on protonation
events during binding, see
http://scorpio2-dev.biophysics.ismb.lon.ac.uk/citation/view/94. |
GENERAL_COMMENT |
| Ambigious error: ΔH - TΔS=-19.81, not equal to ΔG=-20.19 and -R.T.ln(Ka)=-19.846336848312, not equal to ΔG=-20.19 |
INCONSISTENT_DATA |
| Binding too tight to measure directly.
Data obtained by competition ITC. |
GENERAL_COMMENT |
| Calorimetric parameters are reported as the mean value of at least two to three independent experiments, with the reported uncertainty typically being the standard deviation of multiple experiments. |
EXP_ERROR_DET_COMMENT |
| Corrected typo in original paper: table 1, row 4, col 5 changed to 0.83 from -0.83. Deduced from ΔG and ΔH.
Authors contacted |
CORRECTED_INCONSISTENT_DATA |
| Corrected typo in original paper: table 1A, row 1, col 2 changed to -18.3 from -18. Deduced from ΔG, TΔS, and the Ka.
Authors contacted. |
CORRECTED_INCONSISTENT_DATA |
| Corrected typo in original paper: table 2, row 2, col 3 changed to -4.48 from -5.91. Deduced from ΔG, ΔS, the temperature and the plot in figure 2.
Authors contacted. |
CORRECTED_INCONSISTENT_DATA |
| Data are reported as the mean fro two separate titrations with +/- 1 standard deviation in parentheses. |
EXP_ERROR_DET_COMMENT |
| Data based upon five independent isotherms |
EXP_ERROR_DET_COMMENT |
| Data based upon three experiments |
EXP_ERROR_DET_COMMENT |
| Data were fitted to a model assuming one binding site. (Mean +/- S.D. n=3). |
EXP_ERROR_DET_COMMENT |
| Date for average of three experiments, error parameters represent +/- 1 standard deviation. |
EXP_ERROR_DET_COMMENT |
| DeltaG (-14.81) != -R.T.ln(Ka) (-15.16). Tolerance range from -14.96 to -14.66 |
INCONSISTENT_DATA |
| DeltaG (-14.81) greater than -20.00. It is difficult to interpred ITC data if DeltaG is greater than -20.00 as the sigmoidal curve becomes too shallow. |
DUBIOUS_DATA |
