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For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

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DatumProteinLigandΔG (kJ/mol)ΔH (kJ/mol)TΔS (kJ/mol)KD (µM)ΔCp (J/mol)
Link c-Src SH2 Domain acetyl-pYYE-dipentylamine acetyl-pYYE-dipentylamine diagram
acetyl-pYYE-dipentylamine 		-37.24 -17.99 19.09 0.4
Link c-Src SH2 Domain Compound 2, charifson et al. Compound 2, charifson et al. diagram
Compound 2, charifson et al. 		-30.96 -16.32 14.6 4.2
Link c-Src SH2 Domain Compound 3, charifson et al. Compound 3, charifson et al. diagram
Compound 3, charifson et al. 		-33.89 -17.99 15.84 1.4
Link c-Src SH2 Domain acetyl-pYYE-methyl(cyclopentyl-propyl)amine acetyl-pYYE-methyl(cyclopentyl-propyl)amine diagram
acetyl-pYYE-methyl(cyclopentyl-propyl)amine 		-36.82 -29.71 7.11 0.4
Link c-Src SH2 Domain acetyl-pYYE-butylpiperidine acetyl-pYYE-butylpiperidine diagram
acetyl-pYYE-butylpiperidine 		-35.15 -22.59 12.47 1.0
Link c-Src SH2 Domain Compound 6, charifson et al. Compound 6, charifson et al. diagram
Compound 6, charifson et al. 		-31.8 -13.39 18.34 3.4
Link c-Src SH2 Domain Compound 7, charifson et al. Compound 7, charifson et al. diagram
Compound 7, charifson et al. 		-32.64 -19.25 13.35 2.3
Link c-Src SH2 Domain Compound 8, charifson et al. Compound 8, charifson et al. diagram
Compound 8, charifson et al. 		-42.26 -28.45 13.72 0.05
Link c-Src SH2 Domain Compound 9, charifson et al. Compound 9, charifson et al. diagram
Compound 9, charifson et al. 		-41.0 -25.94 14.97 0.09
Link c-Src SH2 Domain Compound 10, charifson et al. Compound 10, charifson et al. diagram
Compound 10, charifson et al. 		-36.82 -21.34 15.34 0.5

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