ITC

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Browse ITC data

For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

DatumProteinLigandΔG (kJ/mol)ΔH (kJ/mol)TΔS (kJ/mol)KD (µM)ΔCp (J/mol)
Link DNA Gyrase B N-Terminal 24 Kda Fragment (variant 2) Novobiocin Novobiocin diagram
Novobiocin
-69.71 -56.48 13.22 0.03
Link DNA Gyrase B N-Terminal 24 Kda Fragment (variant 2) Dihydronovobiocin Dihydronovobiocin diagram
Dihydronovobiocin
-18.94 -30.54 -11.6 0.04
Link DNA Gyrase B N-Terminal 24 Kda Fragment (variant 2) Coumermycin A1 Coumermycin A1 diagram
Coumermycin A1
-40.01 -41.0 -1.0 0.04
Link DNA Gyrase B N-Terminal 24 Kda Fragment (variant 2) Coumermycin A1 Coumermycin A1 diagram
Coumermycin A1
-38.67 -40.17 -1.5 0.05
Link DNA Gyrase B N-Terminal 24 Kda Fragment (variant 2) Clorobiocin Clorobiocin diagram
Clorobiocin
-25.79 -35.15 -9.36 0.02
Link DNA Gyrase B N-Terminal 24 Kda Fragment (variant 2) Clorobiocin Clorobiocin diagram
Clorobiocin
-5.68 -24.27 -18.59 0.03
Link DNA Gyrase B N-Terminal 24 Kda Fragment (variant 2) Clorobiocin Clorobiocin diagram
Clorobiocin
-25.2 -34.31 -9.11 0.02
Link DNA Gyrase B N-Terminal 43 Kda Fragment Novobiocin Novobiocin diagram
Novobiocin
-62.25 -54.39 7.86 0.01
Link DNA Gyrase B N-Terminal 43 Kda Fragment Novobiocin Novobiocin diagram
Novobiocin
-67.34 -56.48 10.85 0.01
Link DNA Gyrase B N-Terminal 43 Kda Fragment Novobiocin Novobiocin diagram
Novobiocin
-63.53 -53.56 9.98 0.02