Browse ITC data
For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.
| Datum | Protein | Ligand | ΔG (kJ/mol) | ΔH (kJ/mol) | TΔS (kJ/mol) | KD (µM) | ΔCp (J/mol) |
|---|
| Link |
Disabled Homolog 1 (native)
|
D-myo-inositol-1,4,5-triphosphate
D-myo-inositol-1,4,5-triphosphate
|
-33.89
|
-80.33
|
-46.44
|
1.2
|
|
| Link |
Disabled Homolog 1 (H81A)
|
D-myo-inositol-1,4,5-triphosphate
D-myo-inositol-1,4,5-triphosphate
|
-27.61
|
-46.86
|
-19.25
|
24.0
|
|
| Link |
Disabled Homolog 1 (H81Q)
|
D-myo-inositol-1,4,5-triphosphate
D-myo-inositol-1,4,5-triphosphate
|
-26.78
|
-41.0
|
-14.23
|
18.0
|
|
| Link |
Disabled Homolog 1 (S114Y)
|
D-myo-inositol-1,4,5-triphosphate
D-myo-inositol-1,4,5-triphosphate
|
-33.89
|
-102.09
|
-68.2
|
1.2
|
|
| Link |
Disabled Homolog 1 (F158V)
|
D-myo-inositol-1,4,5-triphosphate
D-myo-inositol-1,4,5-triphosphate
|
-35.56
|
-75.73
|
-40.17
|
0.6
|
|
