ITC

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Browse ITC data

For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

DatumProteinLigandΔG (kJ/mol)ΔH (kJ/mol)TΔS (kJ/mol)KD (µM)ΔCp (J/mol)
Link DNA Gyrase B N-Terminal 24 Kda Fragment (variant 2) Novobiocin Novobiocin diagram
Novobiocin 		-43.1 -50.63 -7.53 0.03 -1.23
Link DNA Gyrase B N-Terminal 43 Kda Fragment Novobiocin Novobiocin diagram
Novobiocin 		-43.51 -53.14 -9.62 0.03
Link DNA Gyrase B N-Terminal 24 Kda Fragment (variant 2) Novobiocin Novobiocin diagram
Novobiocin 		-41.0 -36.4 4.6 0.03 -1.23
Link DNA Gyrase B N-Terminal 24 Kda Fragment (variant 2) Novobiocin Novobiocin diagram
Novobiocin 		-41.0 -46.44 -5.44 0.05 -1.23
Link DNA Gyrase B N-Terminal 24 Kda Fragment (variant 2) Novobiocin Novobiocin diagram
Novobiocin 		-41.0 -64.85 -23.43 0.09 -1.23
Link DNA Gyrase B N-Terminal 24 Kda Fragment (variant 2) Novobiocin Novobiocin diagram
Novobiocin 		-41.0 -71.13 -30.54 0.13 -1.23
Link DNA Gyrase B N-Terminal 24 Kda Fragment (R136H) Novobiocin Novobiocin diagram
Novobiocin 		-33.89 -73.22 -38.91 1.22 -1.9
Link DNA Gyrase B N-Terminal 24 Kda Fragment (R136H) Novobiocin Novobiocin diagram
Novobiocin 		-33.89 -41.84 -7.95 0.59 -1.9
Link DNA Gyrase B N-Terminal 24 Kda Fragment (R136H) Novobiocin Novobiocin diagram
Novobiocin 		-34.31 -61.5 -27.2 1.0 -1.9
Link DNA Gyrase B N-Terminal 24 Kda Fragment (R136H) Novobiocin Novobiocin diagram
Novobiocin 		-33.05 -75.31 -42.26 2.04 -1.9
Link DNA Gyrase B N-Terminal 24 Kda Fragment (R136H) Novobiocin Novobiocin diagram
Novobiocin 		-32.22 -89.96 -57.74 3.57 -1.9