ITC

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Browse ITC data

For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

DatumProteinLigandΔG (kJ/mol)ΔH (kJ/mol)TΔS (kJ/mol)KD (µM)ΔCp (J/mol)
Link HIV-1 Protease (Q7K/K14R/L63P/V82T/I84V) Amprenavir Amprenavir diagram
Amprenavir
-48.95 -29.29 19.66 0.0
Link HIV-1 Protease (Q7K/K14R/L63P/V82T/I84V) Tmc114 Tmc114 diagram
Tmc114
-57.32 -41.84 15.48 0.0
Link HIV-1 Protease (Q7K/K14R/V82T/I84V) Amprenavir Amprenavir diagram
Amprenavir
-43.93 -16.32 27.61 0.02
Link HIV-1 Protease (Q7K/K14R/V82T/I84V) Tmc126 Tmc126 diagram
Tmc126
-58.99 -40.17 18.83 0.0
Link HIV-1 Protease (Q7K/K14R) Amprenavir Amprenavir diagram
Amprenavir
-52.72 -30.54 22.18 0.0
Link HIV-1 Protease (Q7K/K14R) Tmc114 Tmc114 diagram
Tmc114
-63.6 -50.63 12.97 0.0