ITC

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Browse ITC data

For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

DatumProteinLigandΔG (kJ/mol)ΔH (kJ/mol)TΔS (kJ/mol)KD (µM)ΔCp (J/mol)
Link DNA Gyrase B N-Terminal 43 Kda Fragment Novobiocin Novobiocin diagram
Novobiocin
-43.51 -53.14 -9.62 0.03
Link DNA Gyrase B N-Terminal 43 Kda Fragment Novobiocin Novobiocin diagram
Novobiocin
-44.35 -44.77 -0.42 0.02
Link DNA Gyrase B N-Terminal 43 Kda Fragment Novobiocin Novobiocin diagram
Novobiocin
-62.25 -54.39 7.86 0.01
Link DNA Gyrase B N-Terminal 43 Kda Fragment Novobiocin Novobiocin diagram
Novobiocin
-67.34 -56.48 10.85 0.01
Link DNA Gyrase B N-Terminal 43 Kda Fragment Novobiocin Novobiocin diagram
Novobiocin
-63.53 -53.56 9.98 0.02
Link DNA Gyrase B N-Terminal 43 Kda Fragment Dihydronovobiocin Dihydronovobiocin diagram
Dihydronovobiocin
-30.63 -37.24 -6.61 0.02
Link DNA Gyrase B N-Terminal 43 Kda Fragment Dihydronovobiocin Dihydronovobiocin diagram
Dihydronovobiocin
-19.45 -31.8 -12.35 0.02
Link DNA Gyrase B N-Terminal 43 Kda Fragment Dihydronovobiocin Dihydronovobiocin diagram
Dihydronovobiocin
-39.59 -41.84 -2.25 0.02
Link DNA Gyrase B N-Terminal 43 Kda Fragment Coumermycin A1 Coumermycin A1 diagram
Coumermycin A1
-25.2 -34.31 -9.11 0.02
Link DNA Gyrase B N-Terminal 43 Kda Fragment Coumermycin A1 Coumermycin A1 diagram
Coumermycin A1
-59.9 -51.04 8.86 0.04
Link DNA Gyrase B N-Terminal 43 Kda Fragment Clorobiocin Clorobiocin diagram
Clorobiocin
-31.79 -37.66 -5.86 0.02
Link DNA Gyrase B N-Terminal 43 Kda Fragment Clorobiocin Clorobiocin diagram
Clorobiocin
-35.38 -39.75 -4.37 0.02
Link DNA Gyrase B N-Terminal 43 Kda Fragment Clorobiocin Clorobiocin diagram
Clorobiocin
-8.77 -26.36 -17.59 0.02