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Structure-Calorimetry Of Reported Protein Interactions Online

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Browse ITC data

For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

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Datum	Protein	Ligand	ΔG (kJ/mol)	ΔH (kJ/mol)	TΔS (kJ/mol)	KD (µM)	ΔCp (J/mol)
Link	v-Src SH2 Domain (variant 2)	PQpYEEIPI PQpYEEIPI	-37.66	-31.38	6.28	0.26
Link	v-Src SH2 Domain (variant 2)	PQpYEpYIPI PQpYEpYIPI	-40.58	-29.29	11.3	0.08
Link	v-Src SH2 Domain (variant 2)	PpYEYIPI PpYEYIPI	-35.15	-26.78	8.37	0.67
Link	v-Src SH2 Domain (variant 2)	PQpYIpYVPI PQpYIpYVPI	-36.4	-6.28	30.12	0.4
Link	v-Src SH2 Domain (R207A)	PQpYEEIPI PQpYEEIPI	-35.15	-30.96	4.18	0.67
Link	v-Src SH2 Domain (R207A)	PQpYEpYIPI PQpYEpYIPI	-38.49	-30.96	7.53	0.17
Link	v-Src SH2 Domain (R207A)	PpYEYIPI PpYEYIPI	-34.31	-30.12	4.18	1.0
Link	v-Src SH2 Domain (R207A)	PQpYIpYVPI PQpYIpYVPI	-32.22	-8.37	23.85	1.82
Link	v-Src SH2 Domain (R207F)	PQpYEEIPI PQpYEEIPI	-38.07	-33.05	4.6	0.19
Link	v-Src SH2 Domain (R207F)	PQpYEpYIPI PQpYEpYIPI	-40.58	-28.03	12.55	0.08

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Disclaimer

This is an ongoing project and, although SCORPIO has been curated with great care, it may contain errors. If you spot an error please contact us. We take no responsibility for the data within SCORPIO, nor any responsibility for the consequences of using the data within SCORPIO. No contract, warranty or liability is implied by using the data within SCORPIO.

If you make use of SCORPIO please cite J. Mol. Biol. [2008] 384, 1002-1017
Tjelvar S. G. Olsson, Mark A. Williams, Will R. Pitt and John E. Ladbury