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For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

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DatumProteinLigandΔG (kJ/mol)ΔH (kJ/mol)TΔS (kJ/mol)KD (µM)ΔCp (J/mol)
Link c-Src SH2 Domain acetyl-pYYE-methyl(cyclopentyl-propyl)amine acetyl-pYYE-methyl(cyclopentyl-propyl)amine diagram
acetyl-pYYE-methyl(cyclopentyl-propyl)amine 		-36.82 -29.71 7.11 0.4
Link c-Src SH2 Domain acetyl-pYYE-butylpiperidine acetyl-pYYE-butylpiperidine diagram
acetyl-pYYE-butylpiperidine 		-35.15 -22.59 12.47 1.0
Link c-Src SH2 Domain Compound 6, charifson et al. Compound 6, charifson et al. diagram
Compound 6, charifson et al. 		-31.8 -13.39 18.34 3.4
Link c-Src SH2 Domain Compound 7, charifson et al. Compound 7, charifson et al. diagram
Compound 7, charifson et al. 		-32.64 -19.25 13.35 2.3
Link c-Src SH2 Domain Compound 8, charifson et al. Compound 8, charifson et al. diagram
Compound 8, charifson et al. 		-42.26 -28.45 13.72 0.05
Link c-Src SH2 Domain Compound 9, charifson et al. Compound 9, charifson et al. diagram
Compound 9, charifson et al. 		-41.0 -25.94 14.97 0.09
Link c-Src SH2 Domain Compound 10, charifson et al. Compound 10, charifson et al. diagram
Compound 10, charifson et al. 		-36.82 -21.34 15.34 0.5
Link c-Src SH2 Domain Compound 11, charifson et al. Compound 11, charifson et al. diagram
Compound 11, charifson et al. 		-28.45 -28.45 11.7
Link c-Src SH2 Domain [acetyl]-[deoxy-difluoromethelene-phosphotyrosine]-E-[dipentylamine] [acetyl]-[deoxy-difluoromethelene-phosphotyrosine]-E-[dipentylamine] diagram
[acetyl]-[deoxy-difluoromethelene-phosphotyrosine]-E-[dipentylamine] 		-32.64 -21.34 11.23 2.4
Link c-Src SH2 Domain Compound 13, charifson et al. Compound 13, charifson et al. diagram
Compound 13, charifson et al. 		-38.07 -51.04 -12.85 0.2

1 .. 6 7 8 9 10 .. 12