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For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

DatumProteinLigandΔG (kJ/mol)ΔH (kJ/mol)TΔS (kJ/mol)KD (µM)ΔCp (J/mol)
Link v-Src SH2 Domain (variant 1) pYEEI pYEEI diagram
pYEEI 		-37.7 -25.36 12.35 0.24
Link v-Src SH2 Domain (variant 1) ptc-EEI ptc-EEI diagram
ptc-EEI 		-39.96 -18.74 21.21 0.1 -0.94
Link v-Src SH2 Domain (variant 1) xx2ptc-EEI xx2ptc-EEI diagram
xx2ptc-EEI 		-41.0 -30.67 10.35 0.06 -0.89
Link v-Src SH2 Domain (variant 1) xx1ptc-EEI xx1ptc-EEI diagram
xx1ptc-EEI 		-38.74 -20.96 17.84 0.16
Link v-Src SH2 Domain (variant 1) xx3ptc-EEI xx3ptc-EEI diagram
xx3ptc-EEI 		-40.67 -28.95 11.73 0.07
Link v-Src SH2 Domain (variant 2) PQpYEEIPI PQpYEEIPI diagram
PQpYEEIPI 		-37.66 -31.38 6.28 0.26
Link v-Src SH2 Domain (variant 2) PQpYEpYIPI PQpYEpYIPI diagram
PQpYEpYIPI 		-40.58 -29.29 11.3 0.08
Link v-Src SH2 Domain (variant 2) PpYEYIPI PpYEYIPI diagram
PpYEYIPI 		-35.15 -26.78 8.37 0.67
Link v-Src SH2 Domain (variant 2) PQpYIpYVPI PQpYIpYVPI diagram
PQpYIpYVPI 		-36.4 -6.28 30.12 0.4
Link v-Src SH2 Domain (R207A) PQpYEEIPI PQpYEEIPI diagram
PQpYEEIPI 		-35.15 -30.96 4.18 0.67
Link v-Src SH2 Domain (R207A) PQpYEpYIPI PQpYEpYIPI diagram
PQpYEpYIPI 		-38.49 -30.96 7.53 0.17
Link v-Src SH2 Domain (R207A) PpYEYIPI PpYEYIPI diagram
PpYEYIPI 		-34.31 -30.12 4.18 1.0
Link v-Src SH2 Domain (R207A) PQpYIpYVPI PQpYIpYVPI diagram
PQpYIpYVPI 		-32.22 -8.37 23.85 1.82
Link v-Src SH2 Domain (R207F) PQpYEEIPI PQpYEEIPI diagram
PQpYEEIPI 		-38.07 -33.05 4.6 0.19
Link v-Src SH2 Domain (R207F) PQpYEpYIPI PQpYEpYIPI diagram
PQpYEpYIPI 		-40.58 -28.03 12.55 0.08
Link v-Src SH2 Domain (R207F) PpYEYIPI PpYEYIPI diagram
PpYEYIPI 		-35.56 -30.12 5.44 0.63
Link v-Src SH2 Domain (R207F) PQpYIpYVPI PQpYIpYVPI diagram
PQpYIpYVPI 		-35.98 -7.11 28.87 0.42