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Structure-Calorimetry Of Reported Protein Interactions Online

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For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

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Datum	Protein	Ligand	ΔG (kJ/mol)	ΔH (kJ/mol)	TΔS (kJ/mol)	KD (µM)	ΔCp (J/mol)
Link	Endo-1,4-Beta Glucanase EngF (R92A)	Cellohexaose Cellohexaose	-20.16	-61.97	-41.81	294.12	-0.99
Link	Endo-1,4-Beta Glucanase EngF (N137A)	Cellohexaose Cellohexaose	-20.32	-53.43	-33.11	277.78	-0.88
Link	Streptavidin (synthetic construct)	FSHPQNT FSHPQNT	-22.26	-80.92	-58.58	125.88
Link	Streptavidin (synthetic construct)	HDHPQNL HDHPQNL	-20.25	-79.5	-59.41	282.33
Link	Glutathione S-Transferase 26 Kda (Y7F)	Gluthathione Gluthathione	-28.05	-17.18	10.83	8.6
Link	Glutathione S-Transferase 26 Kda (Y7F)	Gluthathione Gluthathione	-28.13	-22.03	6.1	9.76
Link	Glutathione S-Transferase 26 Kda (Y7F)	Gluthathione Gluthathione	-28.22	-28.72	-0.5	11.42
Link	Glutathione S-Transferase 26 Kda (Y7F)	Gluthathione Gluthathione	-28.13	-34.9	-6.77	14.28
Link	Streptavidin	Biotin Biotin	-76.57	-104.18	-27.61	0.0	-1.44
Link	Circularly Permuted Core-Streptavidin E51/A46	Biotin Biotin	-41.84	-57.74	-15.9	0.04	-0.4
Link	Circularly Permuted Core-Streptavidin E51/A46	Biotin Biotin	-42.26	-56.07	-13.81	0.04
Link	Anti-Tgf Alpha Antibody Fab Fragment	VVSHFND VVSHFND	-43.1	-102.93	-59.83	0.03
Link	v-Src SH2 Domain (variant 2)	PQpYEEIPI PQpYEEIPI	-37.66	-31.38	6.28	0.26
Link	v-Src SH2 Domain (variant 2)	PQpYEpYIPI PQpYEpYIPI	-40.58	-29.29	11.3	0.08
Link	v-Src SH2 Domain (variant 2)	PpYEYIPI PpYEYIPI	-35.15	-26.78	8.37	0.67
Link	v-Src SH2 Domain (variant 2)	PQpYIpYVPI PQpYIpYVPI	-36.4	-6.28	30.12	0.4
Link	v-Src SH2 Domain (R207A)	PQpYEEIPI PQpYEEIPI	-35.15	-30.96	4.18	0.67
Link	v-Src SH2 Domain (R207A)	PQpYEpYIPI PQpYEpYIPI	-38.49	-30.96	7.53	0.17
Link	v-Src SH2 Domain (R207A)	PpYEYIPI PpYEYIPI	-34.31	-30.12	4.18	1.0
Link	v-Src SH2 Domain (R207A)	PQpYIpYVPI PQpYIpYVPI	-32.22	-8.37	23.85	1.82

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Disclaimer

This is an ongoing project and, although SCORPIO has been curated with great care, it may contain errors. If you spot an error please contact us. We take no responsibility for the data within SCORPIO, nor any responsibility for the consequences of using the data within SCORPIO. No contract, warranty or liability is implied by using the data within SCORPIO.

If you make use of SCORPIO please cite J. Mol. Biol. [2008] 384, 1002-1017
Tjelvar S. G. Olsson, Mark A. Williams, Will R. Pitt and John E. Ladbury