SCORPIO version 2.0

Structure-Calorimetry Of Reported Protein Interactions Online

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For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

Datum	Protein	Ligand	ΔG (kJ/mol)	ΔH (kJ/mol)	TΔS (kJ/mol)	KD (µM)	ΔCp (J/mol)
Link	Streptavidin (synthetic construct)	FSHPQNT FSHPQNT	-22.26	-80.92	-58.58	125.88
Link	Streptavidin (synthetic construct)	HDHPQNL HDHPQNL	-20.25	-79.5	-59.41	282.33
Link	Streptavidin	Biotin Biotin	-76.57	-104.18	-27.61	0.0	-1.44
Link	Circularly Permuted Core-Streptavidin E51/A46	Biotin Biotin	-41.84	-57.74	-15.9	0.04	-0.4
Link	Circularly Permuted Core-Streptavidin E51/A46	Biotin Biotin	-42.26	-56.07	-13.81	0.04
Link	Streptavidin (synthetic construct)	HABA HABA	-22.05	7.11	29.16	137.08
Link	Streptavidin (synthetic construct)	Biotin Biotin	-76.57	-133.89	-57.32	0.0
Link	Streptavidin (synthetic construct)	3'-methyl-HABA 3'-methyl-HABA	-30.25	5.36	35.61	5.0
Link	Streptavidin (synthetic construct)	3',5'-dimethyl-HABA 3',5'-dimethyl-HABA	-34.69	9.0	43.68	0.83

Disclaimer

This is an ongoing project and, although SCORPIO has been curated with great care, it may contain errors. If you spot an error please contact us. We take no responsibility for the data within SCORPIO, nor any responsibility for the consequences of using the data within SCORPIO. No contract, warranty or liability is implied by using the data within SCORPIO.

If you make use of SCORPIO please cite J. Mol. Biol. [2008] 384, 1002-1017
Tjelvar S. G. Olsson, Mark A. Williams, Will R. Pitt and John E. Ladbury