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Browse ITC data

For a full dataset and details of experiment click on the datum link or any thermodynamic datum in the table below.

DatumProteinLigandΔG (kJ/mol)ΔH (kJ/mol)TΔS (kJ/mol)KD (µM)ΔCp (J/mol)
Link Ribonuclease T1 Guanosine-5'-monophosphate Guanosine-5'-monophosphate diagram
Guanosine-5'-monophosphate
-22.74 -35.23 -12.49 103.84 -0.26
Link Ribonuclease T1 Guanosine-5'-monophosphate Guanosine-5'-monophosphate diagram
Guanosine-5'-monophosphate
-22.57 -38.91 -16.34 149.48 -0.26
Link Ribonuclease T1 Adenosine-2'-monophosphate Adenosine-2'-monophosphate diagram
Adenosine-2'-monophosphate
-21.82 -31.76 -9.94 80.0 -0.21
Link Ribonuclease T1 Adenosine-2'-monophosphate Adenosine-2'-monophosphate diagram
Adenosine-2'-monophosphate
-21.35 -33.64 -12.28 134.59 -0.21
Link Ribonuclease T1 Adenosine-2'-monophosphate Adenosine-2'-monophosphate diagram
Adenosine-2'-monophosphate
-21.02 -35.9 -14.88 207.47 -0.21
Link Ribonuclease T1 Cytosine-2'-monophosphate Cytosine-2'-monophosphate diagram
Cytosine-2'-monophosphate
-17.24 -31.42 -14.18 578.03 -0.15
Link Ribonuclease T1 Cytosine-2'-monophosphate Cytosine-2'-monophosphate diagram
Cytosine-2'-monophosphate
-16.84 -32.89 -16.04 884.96 -0.15
Link Ribonuclease T1 Cytosine-2'-monophosphate Cytosine-2'-monophosphate diagram
Cytosine-2'-monophosphate
-16.46 -34.39 -17.93 1305.48 -0.15
Link Streptavidin (synthetic construct) HABA HABA diagram
HABA
-22.05 7.11 29.16 137.08
Link Streptavidin (synthetic construct) Biotin Biotin diagram
Biotin
-76.57 -133.89 -57.32 0.0
Link Streptavidin (synthetic construct) 3'-methyl-HABA 3'-methyl-HABA diagram
3'-methyl-HABA
-30.25 5.36 35.61 5.0
Link Streptavidin (synthetic construct) 3',5'-dimethyl-HABA 3',5'-dimethyl-HABA diagram
3',5'-dimethyl-HABA
-34.69 9.0 43.68 0.83